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WGA Rescources

Abstract #10626 Published in IGR 6-2

Acute effects of sildenafil on Humphrey visual field and intraocular pressure

Ermis SS; Inan UU; Samli M; Ozturk F
International Ophthalmology 2004; 25: 69-72


PURPOSE: To evaluate the effects of sildenafil on visual field and intraocular pressure in a group of healthy subjects. METHODS: Twenty-eight healthy male volunteers with normal eyes were included in the study. Visual field examinations were performed using FASTPAC 30-2 program (white-on-white and blue-on-yellow) with the Humphrey field analyzer before and one hour after receiving oral 50 and 100 mg sildenafil citrate. RESULTS: The mean age was 51.1 ± 8.9 years. Mean deviation, pattern standard deviation, short-term fluctuation and corrected pattern standard deviation did not differ significantly among tests both in white-on-white and blue-on-yellow visual field examinations. Changes in intraocular pressure were not statistically significant. CONCLUSIONS: No significant effect of sildenafil was seen on visual field and intraocular pressure in healthy subjects.

Department of Ophthalmology, School of Medicine, University of Afyon Kocatepe, Afyon, Turkey. sametermis@hotmail.com


Classification:

11.15 Other drugs in relation to glaucoma (Part of: 11 Medical treatment)
11.8 Neuroprotection (Part of: 11 Medical treatment)
11.7 Treatment of bloodflow (Part of: 11 Medical treatment)



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