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Abstract #10798 Published in IGR 6-2
Ocular histopathologic observations in Norwegian Elkhounds with primary open-angle, closed-cleft glaucoma
Oshima Y; Bjerkas E; Peiffer RL JrVeterinary Ophthalmology 2004; 7: 185-8
A retrospective histopathologic study of primary glaucoma in the Norwegian Elkhound was undertaken with the study of 9 clinically normal eyes and 22 glaucomatous eyes. All glaucomatous eyes showed goniodysgenesis as manifested by pectinate ligament dysplasia and/or trabecular meshwork dysplasia. Cystic degeneration of the iridociliary epithelial and/or peripheral retina was present in a high percentage of both normotensive and glaucomatous eyes. Utilizing the scheme proposed by Smith et al. (Veterinary and Comparative Ophthalmology 1993; 3: 16-28) the morphology of this disease in the Norwegian Elkhound would be classified as an open-angle, closed-cleft glaucoma, with histopathologic alterations of the outflow pathway similar to that described in other breeds with primary glaucoma.
Department of Ophthalmology, School of Medicine, University of North Carolina, Chapel Hill, NC 27599-7040, USA.
Classification:
5 Experimental glaucoma; animal models