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Abstract #122690 Published in IGR 25-1
Longitudinal outcomes of iStent inject with cataract surgery compared to cataract surgery alone: real-world data from the Fight Glaucoma Blindness registry
Clement CI; Nguyen V; Howes F; Danks J; Lee V; Wechsler D; Roberts EG; Gillies M; Lawlor MJournal of Cataract and Refractive Surgery 2024; 0:
PURPOSE: To compare combined phacoemulsification and iStent inject to phacoemulsification alone. SETTING: Fight Glaucoma Blindness (FGB) registry - Australia. DESIGN: Prospective observational registry study. METHODS: Eyes that had combined phacoemulsification with iStent inject (iStent group) were compared to eyes that had phacoemulsification only (cataract alone). Primary outcome was percentage of eyes achieving >20% IOP reduction from baseline 12 months after surgery. Secondary outcomes included mean IOP and medication reduction, adverse events and secondary procedures. RESULTS: At 12 months the percentage of eyes achieving >20% reduction of IOP at 12 months was significantly higher in the iStent group compared to the cataract alone group (40.9% vs 30.1% p<0.001). Adverse events occurred at a low rate in both groups, and secondary IOP lowering procedures were significantly less frequent in the iStent group compared to cataract alone. CONCLUSIONS: Real-world outcomes from the FGB registry at 12 months show phacoemulsification combined with iStent inject has higher efficacy and a reduced need for secondary IOP lowering surgery compared to phacoemulsification alone.
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