advertisement
Abstract #15362 Published in IGR 1-3
Comparative study of retinal nerve fiber layer damage in Japanese patients with normal- and high-tension glaucoma
Kubota T; Khalik A; Honda M; Ito S; Nishioka Y; Inomata HJournal of Glaucoma 1999; 8: 363-366
PURPOSE: To look for possible differences in the pattern of retinal nerve fiber layer (RNFL) damage induced by normal- and high-tension glaucoma. METHODS: The study included randomly selected eyes from 27 patients with open-angle, high-tension glaucoma (mean age, 54.7±15.0 years; range, 21-74 years) and from 19 age-matched patients with normal-tension glaucoma (mean age, 55.7±11.9 years; range, 35-83 years). Eyes were examined using scanning laser polarimetry. RESULTS: The ratio between the superior and inferior quadrant thickness, or symmetry, was significantly lower in patients with high-tension glaucoma (1.00±0.22) than in patients with normal-tension glaucoma (1.18±0.32). Similarly, the ratio of the superior to the nasal quadrant thickness was significantly lower in patients with high-tension glaucoma (1.56±0.38) than in patients with normal-tension glaucoma (1.80±0.29). No statistically significant differences in the other parameters were detected between the two groups. CONCLUSIONS: These results show that the pattern of RNFL change is different in patients with high- and low-tension glaucoma. The thickness of the RNFL is reduced symmetrically in the superior and inferior quadrants in high-tension glaucoma, whereas a more localized defect on the inferior RNFL occurs in normal-tension glaucoma.
Dr. T. Kubota, Department of Ophthalmology, Nagasaki Chuo National Hospital, Kubara 2-1001-1, Omura City, Nagasaki 856-8562; Japan
Classification:
2.13 Retina and retinal nerve fibre layer (Part of: 2 Anatomical structures in glaucoma)
6.9.1 Laser scanning (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis)
9.2.4 Normal pressure glaucoma (Part of: 9 Clinical forms of glaucomas > 9.2 Primary open angle glaucomas)
