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Abstract #15368 Published in IGR 1-3
Morphology of the optic disc in glaucoma. II. Secondary chronic open-angle glaucomas
Budde WM; Jonas JBKlinische Monatsblätter für Augenheilkunde 1999; 215: 221-227
Previous studies have shown that the chronic open-angle glaucomas form a heterogeneous spectrum of diseases which have in common an open anterior chamber angle and glaucomatous optic nerve damage. The purpose of this study was to evaluate whether the appearance of the optic disc shows specific features among various types of secondary chronic open-angle glaucoma. METHODS: Clinical data and color-stereo optic disc photographs of 126 patients with pseudoexfoliative glaucoma and 47 patients with pigmentary glaucoma were compared with those of 501 patients with primary open-angle glaucoma (POAG) and of 481 normal subjects. The glaucoma groups did not differ in neuroretinal rim or in perimetric mean defect. RESULTS: Mean optic disc area was significantly smaller in the pseudoexfoliative glaucoma eyes (2.54±0.51 mm2 versus 2.71±0.63 mm2, p=0.003) than in the POAG eyes. The pigmentary glaucoma group did not vary significantly from the POAG group in size of the optic disc. No significant differences were found for neuroretinal rim area, configuration of neuroretinal rim, depth of optic cup and diameters of the retinal arterioles and venules at the disc border between the secondary glaucoma groups and the POAG group, respectively. Size of zone beta of the parapapillary atrophy was slightly, but not significantly, smaller in the secondary glaucoma groups than in POAG. In the secondary glaucoma groups, the maximal intraocular pressure measurements were significantly (p < 0.001) higher than in the group with POAG. All glaucoma groups had a significantly smaller neuroretinal rim, significantly smaller retinal arterioles, and significantly larger parapapillary atrophy compared to the normal group. CONCLUSIONS: Except for a slightly smaller optic disc in eyes with pseudoexfoliative glaucoma, eyes with secondary glaucoma due to pseudoexfoliation or pigmentary dispersion do not vary significantly in their optic disc morphology compared to POAG, and do not show pathognomonic features of the optic disc, despite marked changes in the anterior segment of the eye.LA: German
Dr. W.M. Budde, Augenklinik mit Poliklinik der Friedrich-Alexander-Universität-Nürnberg, Schwabachanlage 6, D-91054 Erlangen; Germany
Classification:
2.14 Optic disc (Part of: 2 Anatomical structures in glaucoma)
6.8.2 Posterior segment (Part of: 6 Clinical examination methods > 6.8 Photography)
