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Abstract #15374 Published in IGR 1-3
The relationship between optic disc area and open-angle glaucoma: the Baltimore eye survey
Quigley HA; Varma R; Tielsch JM; Katz J; Sommer A; Gilbert DLJournal of Glaucoma 1999; 8: 347-352
PURPOSE: To determine if eyes with larger optic disc area are more likely to have open-angle glaucoma or to have glaucoma at lower intraocular pressure (IOP). METHODS: Data were collected from a population-based sample of adults residing in East Baltimore, consisting of demographic information, ocular examinations, automated and static/kinetic visual field tests, IOP, as measured by applanation tonometry, and image analysis of the optic disc. Optic disc area was calculated using refractive error to correct magnification. Open-angle glaucoma was defined by visual field and optic disc criteria. One eye from each of 75 patients with glaucoma was compared to those of 3518 subjects without glaucoma. RESULTS: Although optic disc area was somewhat larger among patients with glaucoma than among control subjects, in a regression model adjusting for age, gender, and race, the significance of this difference had a probability of 0.06. Among patients with glaucoma, disc area was not related to IOP level measured at study examination. CONCLUSIONS: Disc area is a weak risk factor for open-angle glaucoma. Disc area did not differ between patients with glaucoma who had lower IOP and those who had higher IOP among a group with glaucoma that were identified in a population survey.
Dr. H.A. Quigley, Wilmer 120, Johns Hopkins Hospital, 600 North Wolfe Street, Baltimore, MD 21287; USA
Classification:
2.14 Optic disc (Part of: 2 Anatomical structures in glaucoma)
9.2.2 Other risk factors for glaucoma (Part of: 9 Clinical forms of glaucomas > 9.2 Primary open angle glaucomas)
