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Abstract #15469 Published in IGR 1-3
Corneal endothelial changes and aqueous flare intensity in pseudoexfoliation syndrome
Wang L; Yamasita R; Hommura SOphthalmologica 1999; 213: 387-391
PURPOSE: To determine the changes of corneal endothelium in pseudoexfoliation (PEX) syndrome and the relationship between their changes and aqueous flare intensity. METHODS: Twenty-six eyes with PEX syndrome, 17 clinically unaffected fellow eyes, and 27 normal age-matched eyes, were studied. The corneal endothelium of the eyes was examined using a specular microscope, and the aqueous flare intensity of the eyes was measured using a laser flare cell meter. RESULTS: The corneal endothelial density significantly decreased both in the eyes with PEX and in the clinically unaffected fellow eyes compared to the normal control eyes (p < 0.001, p < 0.01). The aqueous flare intensity significantly increased in PEX syndrome (p < 0.01). There was a significantly inverse correlation between the corneal endothelial cell density and the aqueous flare intensity in PEX. CONCLUSION: A decrease in corneal endothelial cells was quantitatively identified in PEX syndrome. This change might have a relationship with a disorder of the blood-aqueous barrier in this syndrome.
Dr. L. Wang, Department of Ophthalmology, Doctoral Program in Medical Sciences, Institute of Clinical Medicine, University of Tsukuba, Tsukuba; Japan
Classification:
9.4.4.1 Exfoliation syndrome (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders > 9.4.4 Glaucomas associated with disorders of the lens)
