advertisement
Abstract #17481 Published in IGR 9-2
Clinical features of Graves' ophthalmopathy in Iran
Tari AS; Rajabi MT; Hamzedust K; Tabatabaie SZ; Kasai AInternational Journal of Ophthalmology 2007; 7: 322-326
AIM: To determine the clinical characteristics of a prospective study of patients with Graves' ophthalmopathy. METHODS: We reviewed clinical manifestations, and medical records of 103 patients in whom Graves' ophthalmopathy was diagnosed between 2003 and 2005. RESULTS: Among 103 patients with Graves' ophthalmopathy, 48 (46.6%) male and 55 (53.3%) female (F: M = 1.1), with mean age of 45 (range; 18-73) years, 95 (92.2%) patients had Graves' hyperthyroidism, 3 (2.9%) had primary hypothyroidism, and 5 (4.8%) were euthyroid. The mean duration of ocular symptoms was 13.2 (range 2-95) months) while the mean duration of dysthyroid symptoms was 39.4 (range 6-180) months. Unilaterality was occurred in 12 patients. Eyelid retraction was present in 90 patients (87%), whereas the approximate frequency of exophthalmos was 77.6% (80 patients); restrictive extraocular myopathy, 29% (30 patients); evidence of extraocular enlargement on CT-scan in 52 patients of 70 patients (74%) that was evaluated, and optic nerve dysfunction, 5.8% (6 patients). 22 (21%) patients had glaucoma associated with Graves' ophthalmopathy that 7 (6.7%) of them were normal-tension glaucoma. CONCLUSION: Eyelid retraction was the most common clinical sign of Graves' ophthalmopathy in our patients. Larger prospective studies are suggested to evaluate both the prevalence and possible racial difference in its clinical presentation in Iranian population.
Dr. M.T. Rajabi, Eye Research Center, Farabi Eye Hospital, South Kargar ST, Tehran, Iran. mt_rajabi@yahoo.com
Classification:
9.4.15 Glaucoma in relation to systemic disease (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders)
