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Abstract #19856 Published in IGR 9-4

Tissue adhesive combined with amniotic membrane adhering for ocular surface re-construction

Xu M; Zhang X-B; Kang G-J; Duan C-X
International Journal of Ophthalmology 2007; 7: 1164-1166


AIM: To investigate the usage of tissue adhesive combined with amniotic membrane adhering for ocular surface reconstruction. METHODS: Human amniotic membrane transplantation using tissue adhesive was performed on 17 eyes of 16 patients with ocular surface disorders, including five eyes (four patients) of chemical burns (undergrade IV), four eyes (four patients) of corneal ulcer after ocular trauma, three eyes (three patients) of limited Mooren's ulcer, two eyes (two patients) of corneal ulcer after neuroparalytic keratitis, two eyes (two patients) of exposure keratitis, and one eye (one patient) of absolute glaucoma with bullous keratopathy. All patients received standard medical therapies before surgery. The follow-up time ranged from two to 12 months. Our outcome measures included the local reactions, vision acuity, healing of the epithelial defection, adhering of the tissue adhesive and amniotic membrane. RESULTS: Epithelialization occurred in 88% of the eyes in 9-48 days (mean 26.7 ± 7.8 days). Amniotic membrane attached at about one month. Visual acuity was improved in 83% of the eyes. CONCLUSION: Tissue adhesive combined with amniotic membrane adhering can restore the integrity of the ocular surface in cases which have enough corneal limbus stem cells. It can avoid persistent defect of corneal epithelium and improve the local stimulative symptom. LA: Chinese

Dr. G.-J. Kang, Department of Ophthalmology, Luzhou Medical College, Luzhou 646000 Sichuan Province, China. kanggangjin@sina.com


Classification:

12.20 Other (Part of: 12 Surgical treatment)
2.2 Cornea (Part of: 2 Anatomical structures in glaucoma)



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