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Prostamides are nowadays considered as the most effective drugs used for the long term treatment of primary open angle glaucoma. New prostamides with potential antiglaucoma action were synthesized within the Department of Biosynthesis of Natural Products from the National Institute for Chemical and Pharmaceutical Research and Development, Bucharest. The current research is part of the preliminary toxicological studies and tries to assess the possible histopathological modifications of mice tissues after the treatment with new synthesized prostamides.
D.I. Udeanu. University of Medicine and Pharmacy Carol Davila Bucharest, Faculty of Pharmacy, Department of Clinical Laboratory and Food Safety, Traian Vuia 6, Bucharest 020956, Romania. denisaudeanu@gmail.com
11.4 Prostaglandins (Part of: 11 Medical treatment)
5.1 Rodent (Part of: 5 Experimental glaucoma; animal models)
3.2 Electron microscopy (Part of: 3 Laboratory methods)