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Abstract #24648 Published in IGR 11-4
One-day cross sectional study in Glaucoma
Nordmann JP; Baudouin C; Bron A; Denis P; Renard JP; Rouland JF; Sellem E; Estphan M; Kosa MValue in Health 2009; 12: A458
OBJECTIVES: To assess French patient's characteristics and ophthalmologists management of glaucoma in 2009. METHODS: An internet cross-sectional one-day multicentre study led in France aimed at describing management of glaucoma (G)/ ocular hypertension (OHT) - defined by an intraocular pressure (greater-than or equal to)21 mm Hg, and also at assessing satisfaction and compliance. RESULTS: Two hundred eighty-eight ophthalmologists included 963 patients, 43.2% were male. Open-angle-glaucoma (OAG) in 71.7% and OHT in 24.3% of cases were motives for consultation. For OAG and OHT mean disease duration was respectively 9.2 (plus or minus) 7.7 years and 5.0 (plus or minus) 5.3 years. Mean age was respectively 58.2 (plus or minus) 12.9 and 54.7 (plus or minus) 12.5, mean IOP 17.5 (plus or minus) 4.9 and 19.1 (plus or minus) 4.2 mm Hg. Average treatment duration was 8.0 (plus or minus) 7.1 years, mean number of treatment changes 2.0 (plus or minus) 2.3. Previous treatment consisted in laser in 16.2% of cases, surgery 10.5%, laser plus surgery 4.6%. Medical treatment was administered in 94.0% of OAG patients and in 74.9% of OHT patients. Monotherapy was 50.7% of medical treatment, fixed association 16.4%, non-fixed associations 32.9%. In monotherapy group, beta-blockers (BB) part was 31.7%, prostaglandins (PG) 50.7% and carbonic anhydrase inhibitors CAI 5.9%. In fixed association group BB+PG were used in 72.5% of cases, BB+CAI in 20.3% and BB+ ADR 6.5%. Whatever is the medical treatment, changes are secondary to lack of IOP control, visual field or ocular imaging worsening, lack of tolerance, then weak compliance. Observed rates of very satisfied patients between BB group and PG are as follows: 37.2% CI95 [29.4; 45.8] vs. 28.9% CI95 [23.6; 34.9], rates of very compliant patients: 65.9% CI95 [57.4; 73.5] vs. 61% IC95 [54.7; 66.9]. CONCLUSIONS: This study demonstrated the large part of medical treatment in OAG/OHT. Among them PG are mostly prescribed in monotherapy or fixed association with a high level of satisfaction and compliance according physicians.
J.P. Nordmann. Centre Hospitalier National des Quinze-Vingts, ParisFrance.
Classification:
11.1 General management, indication (Part of: 11 Medical treatment)
11.17 Cooperation with medical therapy e.g. persistency, compliance, adherence (Part of: 11 Medical treatment)