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1 General aspects (0)   1.1 Epidemiology (20)   1.2 Population genetics (3)   1.3 Pathogenesis (0)   1.4 Quality of life (7)   1.5 Glaucomas as cause of blindness (8)   1.6 Prevention and screening (8) 2 Anatomical structures in glaucoma (0)   2.1 Conjunctiva (8)   2.2 Cornea (27)   2.3 Sclera (2)   2.4 Anterior chamber angle (2)   2.5 Meshwork (0)     2.5.1 Trabecular meshwork (8)     2.5.2 Schlemms canal (3)     2.5.3 Scleral outlet channels (0)   2.6 Aqueous humor dynamics (0)     2.6.1 Production (2)     2.6.2 Outflow (1)       2.6.2.1 Trabecular meshwork (5)       2.6.2.2 Uveoscleral (0)     2.6.3 Compostion (8)   2.7 Episcleral veins and venous pressure (0)   2.8 Iris (4)   2.9 Ciliary body (1)   2.10 Lens (1)   2.11 Vitreous body (1)   2.12 Choroid, peripapillary choroid, peripapillary atrophy (3)   2.13 Retina and retinal nerve fibre layer (22)   2.14 Optic disc (22)   2.15 Optic nerve (1)   2.16 Chiasma and retrochiasmal central nervous system (4)   2.17 Stem cells (2)   2.20 Other (0) 3 Laboratory methods (0)   3.1 Microscopy (2)   3.2 Electron microscopy (2)   3.3 Immunohistochemistry (5)   3.4 Molecular genetics (0)     3.4.1 Linkage studies (1)     3.4.2 Gene studies (36)   3.5 Molecular biology incl. 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pharmacoeconomics (6) 15 Miscellaneous (25)

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Abstract #27635 Published in IGR 12-4

Calcium channel blockers: Their use in normal tension glaucoma

Mozaffarieh M; Konieczka K; Flammer J
Expert Review of Ophthalmology 2010; 5: 617-625

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The treatment of normal tension glaucoma can be difficult. Some normal tension glaucoma patients show progression of glaucomatous optic neuropathy despite an intraocular pressure in the normal range, and sometimes even with an intraocular pressure in the low teens. The question therefore arises as to whether there are other therapeutic options besides lowering the intraocular pressure. One treatment modality discussed in the literature is calcium channel blockers. We suspect that calcium channel blockers are particularly useful in glaucoma patients having a primary vascular dysregulation. (copyright) 2010 Expert Reviews Ltd.

J. Flammer. Department of Ophthalmology, University of Basel, Mittlere Strasse 91, CH-4031 Basel, Switzerland. jflammer@uhbs.ch

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Classification:

9.2.4 Normal pressure glaucoma (Part of: 9 Clinical forms of glaucomas > 9.2 Primary open angle glaucomas)
11.14 Investigational drugs; pharmacological experiments (Part of: 11 Medical treatment)

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