advertisement

Topcon

Abstract #3509 Published in IGR 4-2

Five-year incidence of open-angle glaucoma: the visual impairment project

Mukesh BN; McCarty CA; Rait JL; Taylor HR
Ophthalmology 2002; 109: 1047-1051


PURPOSE: To determine the incidence of open-angle glaucoma (OAG) in Melbourne, Victoria, Australia. DESIGN: Population-based cohort study. PARTICIPANTS: Total of 3271 participants aged 40 years and older from Melbourne, Victoria, Australia. MAIN OUTCOME MEASURES: Five-year incidence of OAG. METHODS: Participants were recruited through a cluster random sampling from nine urban clusters. Baseline examination was conducted from 1992-1994, and the follow-up data were collected from 1997-1999. Each participant both at baseline and follow-up underwent a standardized ophthalmic examination including intraocular pressure measurement, visual field assessment, cup-to-disc ratio measurement, and paired stereo photographs of the optic disc. Glaucoma was assessed by a consensus group of six ophthalmologists that included two glaucoma specialists. Glaucoma was diagnosed as possible, probable, or definite. RESULTS: The overall incidence of definite OAG was 0.5% (95% confidence limits (CL), 0.3, 0.7); probable and definite incidence of OAG was 1.1% (95% CL, 0.8,1.4); and possible, probable, and definite OAG incidence was 2.7% (95% CL, 1.8, 3.7). The incidence of possible, probable, and definite OAG increases significantly as age increases (p < 0.001). The incidence of definite OAG increases from 0% of participants aged 40-49 years to 4.1% of participants aged 80 years and older. The incidence of probable and definite OAG increases from 0.2% of participants aged 40-49 years to 5.4% of participants aged 80 years and older. The incidence of possible, probable, and definite OAG increases from 0.5% of participants aged 40-49 years to 11% of participants aged 80 years and older. A nonsignificant but higher incidence of definite OAG among males was observed in this study when compared with women (odds ratio, 2.2; 95% CL, 0.9, 5.9). Fifty percent of the definite OAG participants were undiagnosed. CONCLUSIONS: The incidence of OAG increases significantly with age. The undiagnosed cases suggest the need to develop novel community screening strategies for glaucoma.

Dr. B.N. Mukesh, Centre for Eye Research Australia, the University of Melbourne, Melbourne, Victoria, Australia. mukeshbn@unimelb.edu.au


Classification:

1.6 Prevention and screening (Part of: 1 General aspects)
9.2.3 Open angle glaucoma with elevated IOP (Part of: 9 Clinical forms of glaucomas > 9.2 Primary open angle glaucomas)



Issue 4-2

Change Issue


advertisement

Oculus