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Abstract #45824 Published in IGR 13-2

Neuroprotection in glaucoma

Vasudevan SK; Gupta V; Crowston JG
Indian Journal of Ophthalmology 2011; 59: 102-113


Glaucoma is a neurodegenerative disease characterized by loss of retinal ganglion cells and their axons. Recent evidence suggests that intraocular pressure (IOP) is only one of the many risk factors for this disease. Current treatment options for this disease have been limited to the reduction of IOP; however, it is clear now that the disease progression continues in many patients despite effective lowering of IOP. In the search for newer modalities in treating this disease, much data have emerged from experimental research the world over, suggesting various pathological processes involved in this disease and newer possible strategies to treat it. This review article looks into the current understanding of the pathophysiology of glaucoma, the importance of neuroprotection, the various possible pharmacological approaches for neuroprotection and evidence of current available medications.

S. K. Vasudevan. Faculty of Medicine, Universiti Teknologi MARA, S and T Tower 1, 40450 Shah Alam, Malaysia. Email: sushilvasudevan@yahoo.com


Classification:

11.8 Neuroprotection (Part of: 11 Medical treatment)



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