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Abstract #47018 Published in IGR 13-3

Can topical ketorolac 0.5% improve the function of Ahmed glaucoma drainage devices?

Scott GR; Weizer JS; Moroi SE; Bruno CA; Musch DC; Niziol LM; Lee PP; Stein JD
Ophthalmic Surgery Lasers and Imaging 2011; 42: 190-195

See also comment(s) by Steven Gedde


BACKGROUND AND OBJECTIVE: To determine whether postoperative use of topical ketorolac tromethamine 0.5% affects intraocular pressure (IOP) following Ahmed glaucoma drainage device (New World Medical, Inc., Rancho Cucamonga, CA) implantation. PATIENTS AND METHODS: Patients undergoing Ahmed implantation at the University of Michigan from January 2002 to June 2008 were reviewed. Fourteen eyes received ketorolac after surgery; 50 eyes did not. Preoperative and postoperative IOP and glaucoma medications were recorded for both groups; the two-sided Student's t test was used to compare these parameters. RESULTS: Mean preoperative IOP was similar in the two groups (35.1 (plus or minus) 11.9 vs 37.0 (plus or minus) 12.2 mm Hg; P = .60). At postoperative month 6, the ketorolac group had significantly lower IOP compared with the no ketorolac group (13.1 (plus or minus) 3.7 vs 19.5 (plus or minus) 9.3 mm Hg, respectively; P = .0003). There was no difference in the number of glaucoma medications postoperatively between the two groups. CONCLUSION: Ketorolac may lead to lower postoperative IOP following Ahmed implantation.

J. S. Weizer. 1000 Wall Street, Ann Arbor, MI 48105, United States.


Classification:

12.8.2 With tube implant or other drainage devices (Part of: 12 Surgical treatment > 12.8 Filtering surgery)
11.14 Investigational drugs; pharmacological experiments (Part of: 11 Medical treatment)



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