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Abstract #57514 Published in IGR 16-2

Distal axonopathy in glaucomatous optic neuropathy

Zhang X; Liu S; Yi J
Chinese Journal of Ophthalmology 2014; 50: 391-394

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Glaucoma is a complex class of degenerative optic neuropathy. Multiple mechanisms were involved in glaucomatous optic nerve damage. In recent years, research progression has been made in the relationship between axonal degeneration and glaucoma with more attention and effort dedicated to explicate the pathogenesis of progressive optic nerve injury. Series of studies indicate that the interplay between distal axonal degeneration and axon neuron damage may play an important role in the progression of the disease. Distal axonal lesions may contribute to glaucoma, the pathological basis may be the retrograde degeneration of the optic nerve in visual pathways. In this article, we review the latest findings in the distal axonal degeneration and glaucomatous optic neuropathy.

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Classification:

1.3 Pathogenesis (Part of: 1 General aspects)
11.8 Neuroprotection (Part of: 11 Medical treatment)

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