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Abstract #59223 Published in IGR 16-3
Correlation between central corneal thickness and visual field defect, cup to disc ratio and retinal nerve fiber layer thickness in primary open-angle glaucoma patients
Wangsupadilok B; Orapiriyakul LJournal of the Medical Association of Thailand 2014; 97: 751-757
OBJECTIVE: To assess the correlation between central corneal thickness (CCT) and visual field parameters, cup-to-disc ratio and retinal nerve fiber layer (RNFL) thickness in primary open-angle glaucoma (POAG) patients in Songklanagarind Hospital. MATERIAL AND METHOD: A Retrospective analytical study of the medical records of primary open-angle glaucoma patients, between January 2006 and April 2008, were reviewed. All subjects underwent a complete eye examination. The CCT measurement was performed by ultrasonic pachymeter Mean deviation (MD), pattern standard deviation (PSD), cup-to-disc ratio, and the RNFL thickness of each patient were collected. The correlation coefficient between CCT and MD, PSD, cup-to-disc ratio and RNFL thickness was analyzed. RESULTS: Twenty-six POAG patients (47 eyes) were eligible for the study. Mean age was 60.96 +/- 7.44 years. Average CCT was 511.15 +/- 29.66 microm. Mean AMD and PSD were--10.01 +/- 8.20 and 7.52 +/- 4.43 decibel respectively. Mean cup-to-disc ratio was 0.7 1+/- 0.17. Mean RNFL thickness of superior inferior temporal, nasal quadrants and all quadrants were 101.60 +/- 28.68, 87.15 +/- 32.56, 60.64 +/- 14.14, 61.83 +/- 13.96 and 77.80 +/-17.58 microm, respectively. There were significant correlations between CCT and MD (r = 0.532, p < 0.001), PSD (r = -0.288, p = 0.05), cup-to-disc ratio (r = -0.478, p = 0.001), and average RNFL thickness (r = 0.487, p = 0.001). CONCLUSION: There were significant correlations between CCT and visual field parameters, cup-to-disc ratio, and RNFL thickness.
Classification:
2.2 Cornea (Part of: 2 Anatomical structures in glaucoma)
6.6.2 Automated (Part of: 6 Clinical examination methods > 6.6 Visual field examination and other visual function tests)
2.14 Optic disc (Part of: 2 Anatomical structures in glaucoma)
2.13 Retina and retinal nerve fibre layer (Part of: 2 Anatomical structures in glaucoma)