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Abstract #6023 Published in IGR 2-2
Morphometric changes in optic discs with morphological progression of the glaucomatous optic atrophy measured with laser scanning tomography
Mardin CY; Horn F; Budde WM; Jonas JBKlinische Monatsblätter für Augenheilkunde 2000; 217: 82-87
AIM: To measure morphometric changes in optic discs with scanning laser tomography (HRT, Heidelberg Retina Tomograph, Heidelberg) in eyes with early glaucomatous morphological progression. PATIENTS AND METHODS: Sixty-one eyes of 36 patients with marked neuroretinal rim loss or its early morphological signs (optic disc hemorrhages; reduced visibility of the retinal nerve fiber layer (RNFL); appearance of narrowing of retinal vessels; enlargement of the choroidal, parapapillary atrophy) were compared to 74 normal eyes of 39 probands; 15° stereographs of the optic discs were evaluated for morphological changes. The morphometric variables of the neuroretinal rim and excavation measured by HRT were examined during the course of the disease. RESULTS: In the group of normals, no significant changes of the neuroretinal rim were found during the course of 2.0 ± 1.2 years. In the group of glaucomatous eyes (3.0 ± 1.5 years of follow-up), 34 showed marked neuroretinal rim loss, 17 disc hemorrhages, four vessel narrowing, three increased choroidal atrophy, and three decreased visibility of the RNFL. In these eyes, a significant loss of rim area (p = 0.01) and an increase of excavation area (p = 0.0001) and volume (p = 0.003) was measured by HRT. Only three eyes showed a perimetric loss of sensitivity (0.8-3.4 dB) on Octopus static perimetry. CONCLUSIONS: Scanning laser tomography of the optic disc seems to be able to measure morphometric changes in eyes with morphological progression of glaucomatous optic atrophy, even before perimetric changes occur.
Dr. C.Y. Mardin, Augenklinik mit Poliklinik der Universität Erlangen-Nürnberg, Schwabachanlage 6, 91054 Erlangen, Germany. christian.mardin@augen.imed.uni-erlangen.de
Classification:
2.14 Optic disc (Part of: 2 Anatomical structures in glaucoma)
6.9.1 Laser scanning (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis)
