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Abstract #6106 Published in IGR 2-2

Disk hemorrhage is a significantly negative prognostic factor in normal-tension glaucoma (see comments)

Ishida K; Yamamoto T; Sugiyama K; Kitazawa Y
American Journal of Ophthalmology 2000; 129: 707-714


PURPOSE: The authors investigated the relationship between disc hemorrhage in normal-tension glaucoma and the progression of visual field defects and, additionally, whether hemorrhage plays a role in the pathogenic process of the chronic disease. METHODS: The authors retrospectively reviewed the charts of 70 patients with normal-tension glaucoma (mean follow-up, 5.6 years) who were not medicated for glaucoma, and they applied a regression analysis of survival data based on the Cox proportional hazards model. Several clinical factors were investigated to find a possible association with the progression of glaucomatous visual field defined by two different definitions: one by mean deviation change and the other by glaucoma change probability analysis. RESULTS: Disc hemorrhage, corrected-pattern standard deviation, age, systolic blood pressure, and pulse rate had a significant influence on the visual field defect. The cumulative probability of progression of visual field loss was significantly greater for patients with disc hemorrhage than for patients without disc hemorrhage by either criterion for progression (p

Dr. K. Ishida, Department of Ophthalmology, Gifu University School of Medicine, Gifu-shi, Japan


Classification:

9.2.2 Other risk factors for glaucoma (Part of: 9 Clinical forms of glaucomas > 9.2 Primary open angle glaucomas)



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