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In this case report, the authors describe a 53-year-old woman who was referred as a glaucoma suspect. Five years prior to referral, she reported an allergic response presumed to be associated with ibuprofen that resulted in total loss of the eyelashes and diffuse scalp hair thinning. Her eyebrows and hair from other parts of her body were not affected. Because of the ocular hypertension and the loss of eyelashes, the authors decided to treat her with latanoprost. Three weeks following treatment, eyelashes were noticeable to the patient, and two months later full regrowth of her eyelashes occurred. The authors discuss drug-induced alopecia. In most cases, the hair follicles are not destroyed. It has been suggested that latanoprost treatment may result in hypertrichosis. The authors propose that the dormant hair follicles in their patients were stimulated to enter anagen and growth of eyelashes occurred.
Dr. S.L. Mansberger, Devers Eye Institute/Discoveries in Sight, Portland, OR 97210, USA
11.4 Prostaglandins (Part of: 11 Medical treatment)