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Abstract #79443 Published in IGR 20-2

The heritability of phenotypes related to primary angle closure glaucoma

Yang XH; Qiao CY
Chinese Journal of Ophthalmology 2018; 54: 864-867

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Glaucoma is the leading cause of irreversible blindness throughout the world. Primary angle closure glaucoma (PACG) is one of the common types of this disease. Research indicates that its prevalence is always associated with many factors, including ocular anatomical characteristics and the genetic susceptibility. According to many studies, phenotypes related to PACG, such as anterior chamber depth, relative lens position and thickness, chamber angle state, and axial length, are heritable. Heritability is an important indicator to quantify this genetic tendency. Therefore, the study of heritability plays an important role in explaining the genetic susceptibility and understanding the mechanism of these diseases. This article reviews the heritability of the phenotypes that relate to PACG. -.

Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Sciences Key Lab., Beijing 100730, China.

Full article

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Classification:

1.1 Epidemiology (Part of: 1 General aspects)
1.2 Population genetics (Part of: 1 General aspects)

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