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AIMS: To determine the visual outcome following initiation of brimonidine therapy in glaucoma. METHODS: Sixteen newly diagnosed previously untreated glaucoma patients were randomly assigned to either timolol 0.5% or brimonidine 0.2%. Visual acuity, contrast sensitivity (CS), visual fields, intraocular pressure (IOP), blood pressure, and heart rate were evaluated at baseline and after three months. RESULTS: IOP reduction was similar for both groups (p < 0.05). Brimonidine improved CS; in the right eye at 6 and 12 cpd (p = 0.043, p = 0.017); in the left eye at 3 and 12 cpd (p = 0.044, p = 0.046). Timolol reduced CS at 18 cpd in the right eye (p = 0.041). There was no change in any other measured parameters. CONCLUSION: Glaucoma patients exhibit improved CS on initiation of brimonidine therapy.
Dr. D.W. Evans, School of Optometry, University of Alabama at Birmingham, Birmingham, AL, USA
6.6.3 Special methods (e.g. color, contrast, SWAP etc.) (Part of: 6 Clinical examination methods > 6.6 Visual field examination and other visual function tests)
11.8 Neuroprotection (Part of: 11 Medical treatment)