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Abstract #126619 Published in IGR 25-2

Association between normal tension glaucoma and the risk of obstructive sleep apnoea using the STOP-Bang questionnaire

BACKGROUND: To assess the association between patients with normal tension glaucoma (NTG) and the risk of obstructive sleep apnoea (OSA) using the STOP-Bang questionnaire. METHODS: A population-based cross-sectional analysis was performed using data from the Korean National Health and Nutrition Examination Survey from 2019 to 2021. An overall of 8832 subjects ≥ 40 years of age were investigated. Patients with NTG and controls completed the STOP-Bang questionnaire, a validated tool for identifying high-risk patients for OSA. The patients were divided into low-, intermediate-, and high-risk groups based on their scores. RESULTS: The mean STOP-Bang scores were 2.04 ± 0.02 in the control group and 2.42 ± 0.10 in the NTG group, with significant differences between groups (p < 0.001). In univariate logistic regression models, both intermediate-risk (Odds ratio (OR), 1.42; 95% Confidence intervals (CI), 1.05-1.91) and high-risk (OR, 1.71; 95% CI, 1.22-2.40) for OSA groups revealed a significant relationship regarding NTG compared to low-risk for OSA group. When adjusted for all confounding factors, the high risk for the OSA group was significantly associated with NTG (OR, 1.54; 95% CI, 1.06-2.24). CONCLUSIONS: Our results indicate that high-risk OSA, as measured using the STOP-Bang questionnaire, correlates with NTG. Therefore, patients who scored two or more on the STOP-Bang questionnaire and were male, had a BMI > 35 or a neck circumference > 40 cm, or those who scored five or more and were classified as high risk should be carefully monitored because of the significantly higher likelihood of an association with NTG.

Department of Ophthalmology, Severance Hospital, Institute of Vision Research, Yonsei University College of Medicine, 50 Yonsei‑ro, Seodaemun‑gu, Seoul, South Korea.

Classification:

15 Miscellaneous

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