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Abstract #127519 Published in IGR 25-3

Factors Affecting Bleb Morphology and Postoperative Intraocular Pressure in Inferotemporal PreserFlo MicroShunt Implantation

PURPOSE: To investigate factors associated with bleb morphology and postoperative intraocular pressure (IOP) in eyes with inferotemporal PreserFlo MicroShunt implantation. METHODS: We analyzed 94 eyes that underwent PreserFlo in the inferotemporal quadrant. Slit-lamp photographs of the bleb approximately 6 months after surgery were used for bleb morphology analysis. Bleb vascularity was assessed via two classification criteria. Multivariate analysis was performed to identify factors associated with bleb morphology and 6-month postoperative IOP. RESULTS: The mean age of the patients was 71.6 ± 12.0 years, and 46 patients (64%) were male. Primary open-angle glaucoma was observed in 69 eyes (73%), the mean axial length was 25.4 ± 2.2 mm, and 54 eyes (57%) underwent standalone surgery. The IOP significantly decreased from 24.9 ± 6.8 mm Hg preoperatively to 14.4 ± 2.8 mm Hg at the time of photography (P < 0.001). Avascular blebs were observed in seven eyes (7%) according to both classification systems. There was no significant difference in IOP between avascular and vascularized blebs (13.5 ± 0.9 mm Hg vs. 14.4 ± 2.9 mm Hg; P = 0.08). No preoperative factors predict bleb morphology. Age was the only factor significantly associated with 6-month postoperative IOP (P < 0.001), with a 0.157 mm Hg decrease in IOP for each 1-year increase in age. CONCLUSIONS: Although inferotemporal PreserFlo may result in avascular blebs in a small proportion of patients, postoperative IOP is associated primarily with age rather than with bleb morphology. TRANSLATIONAL RELEVANCE: We provide valuable surgical information for inferotemporal PreserFlo implantation.

Department of Ophthalmology, Saneikai Tsukazaki Hospital, Himeji, Japan.

Classification:

15 Miscellaneous

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