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Abstract #128091 Published in IGR 25-3
A Prospective Study of a New 24-2C Algorithm Using the Swedish Interactive Thresholding Algorithm Standard
Nishijima E; Noro T; Sano K; Ogawa S; Sumi S; Igari Y; Watanabe T; Kishimoto N; Okude S; Lee GC; Iwase A; Nakano TOphthalmology. Glaucoma 2025; 8: 569-579
PURPOSE: To compare the performance of the 24-2C Swedish Interactive Thresholding Algorithm (SITA) Faster and Standard with the 10-2 SITA Standard in assessing visual function in patients with glaucoma. DESIGN: A multicenter prospective cross-sectional study. PARTICIPANTS: Overall, 71 eyes of 71 patients with primary open-angle or normal-tension glaucoma were included. METHODS: The participants underwent visual field testing using the 24-2C SITA Faster, 24-2C SITA Standard (research prototype), and 10-2 SITA Standard in a randomized order on the same day. The global indices, threshold values, total deviation (TD), pattern deviation (PD), and test durations of the algorithms were compared. Correlations among the 10-2 SITA Standard mean deviation (MD) and number of depressed test point locations in the TD and PD probability plots at P < 5%, P < 2%, and P < 1% significance levels within the central 10° were analyzed. MAIN OUTCOME MEASURES: Differences in global indices, threshold values, TD, PD, and test duration between algorithms. Correlations of the MD and number of TD and PD points of the 10-2 SITA Standard and those of the central 10° region for the 24-2C algorithms. RESULTS: No significant differences were found in the global indices between the 24-2C SITA Faster and Standard. The 24-2C SITA Faster had a significantly shorter test duration (55.2% shorter) than the 24-2C SITA Standard. The 24-2C SITA Standard was 45.2% shorter than the combined 24-2 SITA Standard plus 10-2 SITA Standard. The 24-2C SITA Standard showed significantly higher correlation with the 10-2 SITA Standard than the 24-2C SITA Faster. CONCLUSIONS: There were no significant differences in global indices between the 24-2C SITA Standard and 24-2C SITA Faster. However, the 24-2C SITA Standard showed a stronger correlation with the 10-2 SITA Standard. The 24-2C SITA Standard demonstrates potential for more effectively assessing central visual field function in patients with glaucoma. FINANCIAL DISCLOSURE(S): Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.
Department of Ophthalmology, The Jikei University School of Medicine, Nishi-shimbashi, Tokyo, Japan.
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