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Abstract #128503 Published in IGR 25-3
Corneoscleral plaque brachytherapy using 'BARC I-125 Ocu-Prosta seeds' in the management of iridociliary melanoma
Jha UP; Narang S; Jindal VBritish Medical Journal (Clinical Research Edition) Case Reports 2025; 18:
We present the case of a woman in her late 40s who presented with an iris lesion extending to the ciliary body and mature white cataract with a visual acuity of perception of light in her right eye. The tumour was managed with Bhabha Atomic Research Centre Iodine-125 (BARC I-125) Ocu-Prosta seeds plaque therapy with the amniotic membrane buffer technique. No corneal complications or secondary glaucoma were seen over a 6-month follow-up, and a reduction in tumour size was observed on MRI. Ten months post corneoscleral plaque brachytherapy (PB), the patient underwent phacoemulsification in the same eye and achieved a best corrected visual acuity of 20/40. This case highlights the use of cost-effective indigenous I-125 Ocu-Prosta seeds with amniotic membrane in the successful management of iridociliary melanoma, which has not been reported so far.
Department of Ophthalmology, Government Medical College and Hospital, Chandigarh, Chandigarh, India.
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