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Abstract #15333 Published in IGR 1-3
Editorial comment: Vascular or pressure factors in glaucoma?
Cooper RLAustralian and New Zealand Journal of Ophthalmology 1999; 27: 357
this editorial deals with more than only vascular and pressure factors in glaucoma. It covers several other factors which may be involved in the pathogenesis of glaucoma. One of them is the effect of tissue pressure gradient on axoplasmic flow. Optic nerve head tissue pressure and its relationship with other pressures in the retinal vein, retinal artery, intraocular pressure and cerebrospinal fluid pressure was also studied. Variations of optic disc topography by varying intraocular pressure or cerebrospinal fluid pressure were demonstrated. We know that there exist complex relationship between cerebrospinal fluid pressure and tissue pressure gradient in the optic nerve head. This author claims that cerebrospinal fluid pressure may be an important factor influencing the trans optic nerve head pressure gradient. The point this editor tries to make is that with all the different evidence of pathogenetic factors that it is not surprising that there is no absolute relationship between rather sparse measurements of IOP and the diagnosis of progression of glaucoma.
Dr. R.L. Cooper, PO Box 61, Meander, Tas. 7304; Australia ; richardlc@bigpond.com.au
Classification:
1.3 Pathogenesis (Part of: 1 General aspects)
