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Abstract #15357 Published in IGR 1-3
Three-dimensional arrangement of collagen fibrils in human ciliary body
You-Dong Wang; Hai-Bo Chen; Ming Jin; Bo Ou; Kashiwagi K; Tsukahara SOphthalmic Research 1999; 31: 378-386
The purpose of this study is to visualize the three-dimensional arrangement of collagen fibrils in aged human ciliary bodies and to discuss their significance. The ciliary bodies obtained from two human eyes were treated with a NaOH cell-maceration method for seven days, and then prepared conventionally for light and scanning electron microscopy. The general morphology of the collagen tissue in the ciliary body appeared almost the same as that normally observed. Cellular elements were completely removed, but collagen fibrils were well preserved. In the stroma of the ciliary body, collagen fibrils were arranged irregularly. In the areas of the radial and circular ciliary muscles, considerable numbers of collagen fiber bundles were observed running in a circular direction. A honeycomb structure was seen in the pars plana, the walls and base of which were formed by interweaving collagen fibrils. The results suggested that collagen fibrils in the aged human ciliary body may be largely involved in the presbyopia.
Dr. You-Dong Wang, Department of Ophthalmology, Yamanashi Medical University, Tamaho, Yamanashi; Japan
Classification:
2.9 Ciliary body (Part of: 2 Anatomical structures in glaucoma)
3.2 Electron microscopy (Part of: 3 Laboratory methods)
