Abstract #47018 Published in IGR 13-3

Can topical ketorolac 0.5% improve the function of Ahmed glaucoma drainage devices?

Scott GR; Weizer JS; Moroi SE; Bruno CA; Musch DC; Niziol LM; Lee PP; Stein JD
Ophthalmic Surgery Lasers and Imaging 2011; 42: 190-195

See also comment(s) by Steven Gedde

BACKGROUND AND OBJECTIVE: To determine whether postoperative use of topical ketorolac tromethamine 0.5% affects intraocular pressure (IOP) following Ahmed glaucoma drainage device (New World Medical, Inc., Rancho Cucamonga, CA) implantation. PATIENTS AND METHODS: Patients undergoing Ahmed implantation at the University of Michigan from January 2002 to June 2008 were reviewed. Fourteen eyes received ketorolac after surgery; 50 eyes did not. Preoperative and postoperative IOP and glaucoma medications were recorded for both groups; the two-sided Student's t test was used to compare these parameters. RESULTS: Mean preoperative IOP was similar in the two groups (35.1 (plus or minus) 11.9 vs 37.0 (plus or minus) 12.2 mm Hg; P = .60). At postoperative month 6, the ketorolac group had significantly lower IOP compared with the no ketorolac group (13.1 (plus or minus) 3.7 vs 19.5 (plus or minus) 9.3 mm Hg, respectively; P = .0003). There was no difference in the number of glaucoma medications postoperatively between the two groups. CONCLUSION: Ketorolac may lead to lower postoperative IOP following Ahmed implantation.

J. S. Weizer. 1000 Wall Street, Ann Arbor, MI 48105, United States.


12.8.2 With tube implant or other drainage devices (Part of: 12 Surgical treatment > 12.8 Filtering surgery)
11.14 Investigational drugs; pharmacological experiments (Part of: 11 Medical treatment)

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