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Abstract #6004 Published in IGR 2-2
Nerve fibre layer measurement of the Hong Kong Chinese population by scanning laser polarimetry
Lee VW; Mok KHEye 2000; 14: 371-374
PURPOSE: To obtain normal retinal nerve fiber layer (RNFL) measurements by scanning laser polarimetry in a local Hong Kong Chinese population and to identify the correlation of the measurements with age. METHODS: One hundred and fifty-nine normal Hong Kong Chinese volunteers of different ages were recruited for this study. RNFL values were measured using a nerve fiber analyzer GDx (Laser Diagnostic Technologies, CA). RESULTS: Mean peripapillary RNFL measurements at the superior, inferior, temporal and nasal regions were 95.0 ± 15.6, 97.0 ± 16.3, 47.0 ± 9.0, and 43.9 ± 15.1 μm, respectively (mean ± SD). There was a highly significant negative correlation in average RNFL values with increasing age (-1.9 μm per decade, p = 0.001). A significant negative correlation with increasing age was also identified in the RNFL values in all four regions, and they decreased by similar amounts (p < 0.05). No correlation with age was observed for relative ratio parameters such as superior/nasal ratio, inferior/nasal ratio, and maximum modulation (p > 0.05). CONCLUSIONS: RNFL values of the Hong Kong Chinese population appeared to decrease over time cross-sectionally. Since they decreased by similar amounts at four regions, use of relative ratio parameters for analysis has an advantage over absolute values, as they were not affected by age.
Dr. V.W. Lee, Eye Centre, Hong Kong Adventist Hospital, 40 Stubbs Road, Hong Kong. vinwhlee@hkah.org.hk
Classification:
2.13 Retina and retinal nerve fibre layer (Part of: 2 Anatomical structures in glaucoma)
6.9.1 Laser scanning (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis)
