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Abstract #6007 Published in IGR 2-2
Longitudinal changes in retinal nerve fiber thickness in glaucoma eyes
Takahashi I; Tanaka MJapanese Journal of Clinical Ophthalmology 2000; 54: 1071-1076
The authors examined the retinal nerve fiber layer thickness (RNFLT) in 87 eyes. The series comprised primary open-angle glaucoma (POAG; 39 eyes), normal-tension glaucoma (NTG; 24 eyes), and 24 normal eyes. RNFLT was measured by a nerve fiber analyzer GDx™ at six-month intervals up to 12 months. The visual field was evaluated for MD value using a Humphrey automated perimeter initially and at 12 months. There was no change in RNFLT at six months. Significant changes were present at 12 months regarding Inf Max, Inf Ratio and Max M in POAG eyes and Sup Max in NTG eyes. The MD value showed a significant decrease at 12 months in NTG eyes only. There was no significant difference in initial MD value between early POAG and NTG eyes with MD value of -5.0 dB or greater. The findings show that RNFLT in the inferior sector may be decreased in POAG eyes before manifest field defect shows progression. LA: Japanese
Dr. I. Takahashi, Department of Ophthalmology, Juntendo University, Urayasu Hospital, 2-1-1 Tomioka, Urayasu-shi 279-0021, Japan
Classification:
2.13 Retina and retinal nerve fibre layer (Part of: 2 Anatomical structures in glaucoma)
6.9.1 Laser scanning (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis)
