advertisement
Abstract #6068 Published in IGR 2-2
Central and regional hemodynamics of eyes in different course of primary open-angle glaucoma with normalized intraocular pressure and their relationship with circulation types, sympathoadrenal activity and hydrocortisone level
Egorov VV; Sorokin EL; Smoliakova GPVestnik Oftalmologii 2000; 116: 3-5
The relationship between systemic and local hemodynamics and neurohumoral factors was evaluated in 104 patients with primary open-angle glaucoma with normalized intraocular pressure. Changes in the functional activity of the sympathoadrenal activity and hydrocortisone levels were in close correlation with the initial type of systemic hemodynamics: the hormonal activity of the sympathoadrenal system predominated in patients with eukinetic and hyperkinetic circulation with normal levels of hydrocortisone, while in patients with hypokinetic circulation, the mediator (norepinephrine) component of the sympathoadrenal system combined with a high plasma level of hydrocortisone predominated. A principal characteristic of unstable primary open-angle glaucoma, discriminating it from the stable condition in all types of circulation, is the presence of deep autonomical disorders in the neurohumoral mechanisms of the autoregulation of the ocular blood flow, because of the excessive accumulation of norepinephrine, epinephrine, and hydrocortisone in the lacrimal fluid at the expense of their decreased utilization by the receptor systems of ocular tissues and blood vessels. LA: Russian
Classification:
6.11 Bloodflow measurements (Part of: 6 Clinical examination methods)
