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Abstract #73579 Published in IGR 18-4
The association between glaucoma, anxiety and depression in a large population
Zhang X; Olson DJ; Le P; Lin FC; Fleischman D; Davis RMAmerican Journal of Ophthalmology 2017; 183: 37-41
PURPOSE: To investigate the association between glaucoma and each of anxiety and depression. DESIGN: Retrospective case-control study. METHODS: Settings: University of North Carolina hospitals and outpatient clinics. STUDY POPULATION: All patients over the age of 18 years seen between July 1, 2008 and October 1, 2015 were included. OBSERVATION PROCEDURE: International classification of disease codes were used to identify cases of glaucoma, as well as anxiety and depression. OUTCOME MEASURE: Odds ratios (OR) were calculated for glaucoma and each of anxiety and depression. OR were also calculated for above diagnoses separated by age group and sex. RESULTS: A total of 4,439,518 patients were screened, of which 11,234 (0.3%) have glaucoma, 96,527 (2.2%) have anxiety, and 103,476 (2.3%) have depression. The adjusted OR was 10.6 (95% confidence interval [CI] 10.0-11.0) for glaucoma and anxiety and 12.3 (95% CI 11.8-12.9) for glaucoma and depression. The likelihood of having anxiety and depression along with glaucoma did not change with age (p=0.088, p=0.736) CONCLUSION: There was a statistically significant association between glaucoma and each of anxiety and depression.
University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA, 321 South Columbia Street, Chapel Hill, NC 27514.
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