Abstract #86105 Published in IGR 21-2

Comparison of early versus late laser goniopuncture following deep sclerectomy for the management of open-angle glaucoma

Holmes D; Hui MMP; Clement C
British Journal of Ophthalmology 2020; 104: 1384-1389

PURPOSE: To compare the outcome of early versus late Nd:YAG laser goniopuncture (LGP) after deep sclerectomy with mitomycin C (DSMMC) for open-angle glaucoma (OAG). METHODS: A retrospective study of consecutive OAG eyes that underwent a LGP following DSMMC was recruited between June 2012 and November 2015. Success was defined as intraocular pressure (IOP) less than 21, 18 or 15 mm Hg with a reduction of more than 20% IOP from baseline without (complete success) or with medications (qualified success). RESULTS: 99 eyes with OAG that underwent DSMMC were recruited into the study. Of these, 49 eyes (49.49%) had undergone LGP post-DSMMC. IOP was significantly reduced following LGP from 28.4 to 11.8 mm Hg. Comparison of Kaplan-Meier survival curves out to 60 months after LGP showed a trend towards better outcomes in the late LGP group with the only statistically significant difference noted for qualified success with IOP target <15 mm Hg. Complications were few with no difference noted between early and late LGP groups. CONCLUSION: There appears to be a trend towards late LGP being more effective after DSMMC when compared with early LGP; this however was not significant. This study corroborates previous published data confirming LGP is an effective and safe procedure for lowering IOP post-DSMMC procedure.

Faculty of Medicine, University of Sydey, Camperdown, New South Wales, Australia

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12.8.3 Non-perforating (Part of: 12 Surgical treatment > 12.8 Filtering surgery)
12.4 Laser trabeculoplasty and other laser treatment of the angle (Part of: 12 Surgical treatment)

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