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PURPOSE: To assess the relationship between smoking and intraocular pressure (IOP). MATERIAL AND METHODS: The Blue Mountains Eye Study examined 3654 residents aged 49 years and older in an area west of Sydney, Australia from 1992 to 1994. A trained interviewer collected a detailed history of smoking. IOP was measured using Goldmann applanation tonometry; as the correlation between right and left eyes was very high, only right-eye data are presented. Participants using glaucoma medications or who had evidence of previous cataract surgery were excluded. RESULTS: Current smokers (15.8% of participants) had slightly higher mean IOPs (16.34 mmHg) than nonsmokers (16.04 mmHg). IOP (in the right eye) was significantly associated with current smoking, after adjusting for age and sex (p = 0.03). This association remained unchanged after simultaneous adjustment for other variables associated with IOP, including blood pressure, diabetes, myopia, glaucoma, family history, and pseudoexfoliation (p = 0.02). CONCLUSION: This study identified a modest cross-sectional positive association between current smoking and IOP.
Dr. P. Mitchell, University of Sydney Department of Ophthalmology (Center for Vision Research), Westmead, Hospital, Hawkesbury Road, Westmead, NSW Australia 2145. paulmi@westgate.wh.usyd.edu.au
1.1 Epidemiology (Part of: 1 General aspects)
9.2.2 Other risk factors for glaucoma (Part of: 9 Clinical forms of glaucomas > 9.2 Primary open angle glaucomas)