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Abstract #15628 Published in IGR 1-3
Pathogenesis and conservative treatment of glaucoma
Süveges IOrvosi Hetilap 1999; 140: 2211-2214
Glaucoma is a chronic disease which, if not treated, can lead to blindness. The reason for deterioration of function is neuropathia n. optici developed during the disease. Previously, increased ocular tension was considered to be the cause of neuropathia. By now we have realized that increased ocular tension (that above 21 mmHg) in only one of the risk factors. The decay of optic nerve fibers is caused by circulatory failure on the one hand, and by the necrosis of ganglion cells on the other. In the conservative treatment of glaucoma, pilocarpin was used previously, but nowadays the first place has been taken over by the group of beta-receptor blockers, which are applied twice a day in the form of dropping. If this proves unsatisfactory, the treatment is complemented with carbonanhydrase inhibitor drops two to three times daily. In certain cases, this is followed by prostaglandin F2α analogue drops once a day, in the evening. Carboanhydrase inhibitor can be administered per oral as well: once or twice weekly. This latter cannot be given continuously: it is only a temporal solution for a few months in addition to other conservative therapy. Cholinergic drops can be added at any time during conservative treatment. The future method of conservative therapy is the combination of drops with various effect, which decreases the frequency of daily drops and enhances the efficacy of treatment.LA: Hungarian
Dr. I. Suveges, I. sz. Szemeszeti Klinika, Semmelweis Orvostudomanyi Egyetem, Budapest; Hungary
