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Abstract #6079 Published in IGR 2-2
Ultrasound biomicroscopic analysis of the human ciliary body after 1 and 2% pilocarpine instillation
Arakawa A; TamaiOphthalmologica 2000; 214: 253-259
The authors examined ciliary body thickness (CBT) in 11 human eyes after 1% followed by 2% pilocarpine instillation, using ultrasound biomicroscopy. The examination revealed that CBT decreased in two eyes after 1% pilocarpine treatment, but increased after 2% pilocarpine. In the eyes with decreased CBT after 1% pilocarpine, the pretreatment ciliary bodies were thicker and the changing rate of CBT induced by 2% pilocarpine, although not decreased, was also smaller than that in CBT-increased eyes. These findings showed that the ciliary body was under the relatively strong stimulus of endogenous acetylcholine, and has subsensitivity to both 1% and 2% pilocarpine in CBT-decreased eyes. The configurative changes in CBT-decreased eyes may be explained by the localization of different muscarinic receptor subtypes in different portions of the ciliary muscle.
Dr. A. Arakawa, Department of Ophthalmology, Tohoku University School of Medicine, Sendai, Miyagi, Japan
Classification:
6.12 Ultrasonography and ultrasound biomicroscopy (Part of: 6 Clinical examination methods)
