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119431 Autophagy deficiency protects against ocular hypertension and glaucoma
Dixon A; Shim MS; Nettesheim A; Coyne A; Su CC; Gong H; Liton PB
Autophagy reports 2024; 3: (IGR: 25-1)
108342 AUTOPHAGY IN THE EYE: FROM PHYSIOLOGY TO PATHOPHYSOLOGY
Liton PB; Boesze-Battaglia K; Boulton ME; Boya P; Ferguson TA; Ganley IG; Kauppinnen A; Laurie GW; Mizushima N; Morishita H; Russo R; Sadda J; Shyam R; Sinha D; Thompson DA; Zacks DN
Autophagy reports 2023; 2: (IGR: 23-4)
99343 The physiological and pathophysiological roles of the autophagy lysosomal system in the conventional aqueous humor outflow pathway: More than cellular clean up
Shim MS; Liton PB
Progress in Retinal and Eye Research 2022; 0: 101064 (IGR: 22-4)
91615 Cathepsin B Localizes in the Caveolae and Participates in the Proteolytic Cascade in Trabecular Meshwork Cells. Potential New Drug Target for the Treatment of Glaucoma
Nettesheim A; Shim MS; Dixon A; Raychaudhuri U; Gong H; Liton PB
Journal of clinical medicine 2020; 10: (IGR: 21-4)
84486 Transcriptome analysis reveals autophagy as regulator of TGFβ/Smad-induced fibrogenesis in trabecular meshwork cells
Nettesheim A; Shim MS; Hirt J; Liton PB
Scientific reports 2019; 9: 16092 (IGR: 21-1)
78295 Contribution of autophagy to ocular hypertension and neurodegeneration in the DBA/2J spontaneous glaucoma mouse model
Hirt J; Porter K; Dixon A; McKinnon S; Liton PB
Cell death discovery 2018; 5: 14 (IGR: 19-4)
69271 Autophagy and mechanotransduction in outflow pathway cells
Hirt J; Liton PB
Experimental Eye Research 2017; 158: 146-153 (IGR: 18-1)
61513 The autophagic lysosomal system in outflow pathway physiology and pathophysiology
Liton PB
Experimental Eye Research 2016; 144: 29-37 (IGR: 17-1)
60073 Autophagic dysregulation in glaucomatous trabecular meshwork cells
Porter K; Hirt J; Stamer WD; Liton PB
Biochimica et Biophysica Acta 2015; 1852: 379-385 (IGR: 16-4)
56321 Ascorbic acid modulation of iron homeostasis and lysosomal function in trabecular meshwork cells
Xu P; Lin Y; Porter K; Liton PB
Journal of Ocular Pharmacology and Therapeutics 2014; 30: 246-253 (IGR: 16-1)
56368 MTOR-independent induction of autophagy in trabecular meshwork cells subjected to biaxial stretch
Porter KM; Jeyabalan N; Liton PB
Biochimica et Biophysica Acta 2014; 1843: 1054-1062 (IGR: 16-1)
53059 Lysosomal basification and decreased autophagic flux in oxidatively stressed trabecular meshwork cells: implications for glaucoma pathogenesis
Porter K; Nallathambi J; Lin Y; Liton PB
Autophagy 2013; 9: 581-594 (IGR: 15-1)
27050 Intralysosomal iron induces lysosomal membrane permeabilization and cathepsin d-mediated cell death in trabecular meshwork cells exposed to oxidative stress.
Lin Y; Epstein DL; Liton PB
Investigative Ophthalmology and Visual Science 2010; 51: 6483-6495 (IGR: 12-4)
23711 The role of proteolytic cellular systems in trabecular meshwork homeostasis
Liton PB; Gonzalez P; Epstein DL
Experimental Eye Research 2009; 88: 724-828 (IGR: 11-2)
23002 Potential role of lysosomal dysfunction in the pathogenesis of primary open angle glaucoma
Liton PB; Lin Y; Gonzalez P; Epstein DL
Autophagy 2009; 5: 122-124 (IGR: 11-1)
22847 Resveratrol prevents the expression of glaucoma markers induced by chronic oxidative stress in trabecular meshwork cells
Luna C; Li G; Liton PB; Qiu J; Epstein DL; Challa P; Gonzalez P
Food and Chemical Toxicology 2009; 47: 198-204 (IGR: 11-1)
21874 Stress response of the trabecular meshwork
Liton PB; Gonzalez P
Journal of Glaucoma 2008; 17: 378-385 (IGR: 10-3)
21779 Cultured porcine trabecular meshwork cells display altered lysosomal function when subjected to chronic oxidative stress
Liton PB; Lin Y; Luna C; Li G; Gonzalez P; Epstein DL
Investigative Ophthalmology and Visual Science 2008; 49: 3961-3969 (IGR: 10-3)
20632 Sustained stress response after oxidative stress in trabecular meshwork cells
Li G; Luna C; Liton PB; Navarro I; Epstein DL; Gonzalez P
Molecular Vision 2007; 13: 2282-2288 (IGR: 10-1)
20638 Effect of cellular senescence on the P2Y-receptor mediated calcium response in trabecular meshwork cells
Chow J; Liton PB; Luna C; Wong F; Gonzalez P
Molecular Vision 2007; 13: 1926-1933 (IGR: 10-1)
14761 Genome-wide expression profile of human trabecular meshwork cultured cells, nonglaucomatous and primary open angle glaucoma tissue
Liton PB; Luna C; Challa P; Epstein DL; Gonzalez P
Molecular Vision 2006; 12: 774-790 (IGR: 8-4)
13760 Characterization of free-floating spheres from human trabecular meshwork (HTM) cell culture in vitro
Gonzalez P; Epstein DL; Luna C; Liton PB
Experimental Eye Research 2006; 82: 959-967 (IGR: 8-2)
13697 Lentiviral mediated gene delivery to the anterior chamber of rodent eyes
Challa P; Luna C; Liton PB; Chamblin B; Wakefield J; Ramabhadran R; Epstein DL; Gonzalez P
Molecular Vision 2005; 11: 425-430 (IGR: 8-2)
13274 Induction of TGF-β1 in the trabecular meshwork under cyclic mechanical stress
Liton PB; Liu X; Challa P; Epstein DL; Gonzalez P
Journal of Cellular Physiology 2005; 205: 364-371 (IGR: 8-1)
12549 Cellular senescence in the glaucomatous outflow pathway
Liton PB; Challa P; Stinnett S; Luna C; Epstein DL; Gonzalez P
Experimental Gerontology 2005; 40: 745-748 (IGR: 7-3)