Medical Treatment: Investigational drugs (16-4, September 2015) on:
60077 Intra-ocular pressure-lowering effects of a Rho kinase inhibitor, ripasudil (K-115), over 24 hours in primary open-angle glaucoma and ocular hypertension: a randomized, open-label, crossover study
Tanihara H; Inoue T; Yamamoto T et al.
Acta Ophthalmologica 2015; 93: e254-e260
Comments (16-3, June 2015) on:
59479 Induced pluripotent stem cells restore function in a human cell loss model of open-angle glaucoma
Abu-Hassan DW; Li X; Ryan EI et al.
Stem Cells 2015; 33: 751-761
Basic Research: IOP regulators (13-4, April 2012) on:
48121 eNOS, a Pressure-Dependent Regulator of Intraocular Pressure
Stamer W; Lei Y; Boussommier-Calleja A et al.
Investigative Ophthalmology and Visual Science 2011; 52: 9438-9444
Basic Research Animal Studies: Aqueous humor dynamics in OH monkeys (12-4, March 2011) on:
27132 Aqueous humor dynamics in inbred rhesus monkeys with naturally occurring ocular hypertension
Toris CB; Risma JM; Gonzales-Martinez J et al.
Experimental Eye Research 2010; 91: 860-865
Medical Treatment: Prostaglandin pathway gene therapy (11-4, March 2010) on:
24688 Prostaglandin Pathway Gene Therapy for Sustained Reduction of Intraocular Pressure
Barraza RA; McLaren JW; Poeschla EM
Molecular Therapy 2010; 18: 491-501
Basic research: Best2 and IOP (10-2, September 2008) on:
21024 Bestrophin-2 is involved in the generation of intraocular pressure
Bakall B; McLaughlin P; Stanton JB et al.
Investigative Ophthalmology and Visual Science 2008; 49: 1563-1570
Medical treatment: ROCK inhibition (10-1, July 2008) on:
20766 Intraocular Pressure-Lowering Effects and Safety of Topical Administration of a Selective ROCK Inhibitor, SNJ-1656, in Healthy Volunteers
Tanihara H; Inatani M; Honjo M et al.
Archives of Ophthalmology 2008; 126: 309-315
Medical Therapy: PG and outflow pathways (9-3, December 2007) on:
19603 Bimatoprost, prostamide activity, and conventional drainage
Wan Z; Woodward DF; Cornell CL et al.
Investigative Ophthalmology and Visual Science 2007; 48: 4107-4115
Medical treatment: Extrascleral PG (9-1, June 2007) on:
16969 Direct matrix metalloproteinase enhancement of transscleral permeability
Lindsey JD; Crowston JG; Tran A et al.
Investigative Ophthalmology and Visual Science 2007; 48: 752-755
Medical treatment: PGF2a and fluprostenol (8-1, June 2006) on:
13527 Endothelin Antagonism: Effects of FP Receptor Agonists Prostaglandin F2α and Fluprostenol on Trabecular Meshwork Contractility
Thieme H; Schimmat C; Munzer G et al.
Investigative Ophthalmology and Visual Science 2006; 47: 938-945
Basic science: Animal models (7-3, March 2006) on:
13191 Repeat sample intraocular pressure variance in induced and naturally ocular hypertensive monkeys
Dawson WW; Dawson JC; Hope GM et al.
Journal of Glaucoma 2005; 14: 426-431
Basic Reseach: RHO-kinase inhibitor (7-2, November 2005) on:
12242 Contribution of ROCK in contraction of trabecular meshwork: Proposed mechanism for regulating aqueous outflow in monkey and human eyes
Nakajima E; Nakajima T; Minagawa Y et al.
Journal of Pharmaceutical Sciences 2005; 94: 701-708