Top-ten American Glaucoma Society meeting
San Diego, CA, USA, March 5-8, 2009
Anne Coleman and Gustavo de Moraes
Clinical disc margin anatomy in nonhuman primates can be
detected with the spectral-OCT but is complicated and dependent upon
the internally or externally oblique orientation of the border
tissue of Elschnig. (Claude Burgoyne, Portland, OR, USA)
Eyes presenting with initial glaucomatous damage in both
hemifields progress more rapidly and are more likely to have
progressive damage than those with the initial damage limited to one
hemifield only. (Gustavo De Moraes, New York, NY, USA)
Higher intraocular pressure levels are associated with a faster
rate of progressive change of the retinal nerve fiber layer
thickness as measured with GDx ECC. Eyes with documented progression
on visual fields and/or disc photographs show significantly faster
rates of nerve fiber loss. (Felipe Medeiros, La Jolla, CA, USA)
Glaucoma topical treatment adherence improves significantly
following interventions such as watching videos, interacting with
study coordinators, receiving regular phone call reminders, and
turning on an alarm reminder to take drops. (David S. Friedman,
Baltimore, MD, USA)
In an experimental animal model, diet modification alters the
optic nerve response to intraocular pressure induced oxidative
stress. (Jonathan Crowston, Melbourne, Australia)
Although micronutrients (in general) have theoretical potential,
they have not been systematically studied for use as therapeutic
agents for glaucoma. (Robert N. Weinreb, La Jolla, CA, USA)
Ophthalmic adaptive optics technology allows in vivo,
non-invasive imaging of the cone photoreceptor mosaic, the retinal
pigment epithelial cell mosaic, capillary vasculature and individual
leukocyte capillary flow, which has a potential use for the
diagnosis and treatment of various ocular conditions. (Alfredo Dubra,
Rochester, NY, USA)
High resolution, in vivo imaging of the human retina, will allow
for significant advances in early disease detection, assessment of
factors that promote ganglion cell death or survival, and
substantially shorten the time required to assess new therapies
designed to protect the optic nerve or enhance visual function.
(Jeffrey M. Liebmann, New York, NY, USA)
Despite presenting with similar intraocular pressure reduction
from baseline and use of medical therapy, tube shunt surgery is more
likely to maintain intraocular pressure control and avoid persistent
hypotony, reoperation for glaucoma, or loss of light perception
vision compared with trabeculectomy with MMC during the first 3
years of this multicenter, randomized clinical trial. (Steven J.
Gedde, Miami, FL, USA)
A meta-analysis of the major cohorts does not support an
association between primary open angle glaucoma and increased risk
of death. (Louis R. Pasquale, Boston, MA, USA)