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Top X from the 11th annual scientific meeting of the Japanese Glaucoma Society
Kobe, Japan, September 1st-3rd, 2000
M. Araie
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In Japanese eyes, an increase in iris pigmentation was noticeable after one month's use of latanoprost, and after six months, 14.7% of 86 eyes showed iris pigmentation to some degree.
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In another report, latanoprost increased the length of the cilium in ten of 16 eyes after a follow-up of six months or longer.
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However, latanoprost may improve ocular blood flow in normal-tension glaucoma patients by increasing the peak systolic and end diastolic blood velocity of the short posterior ciliary arteries and the central retinal artery following an increase of ocular perfusion pressure.
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A mutation of the CYP1B1 gene was observed in 12% of 60 families with congenital glaucoma, and in four subtypes of mutations, Val364Met seemed to be of Japanese origin.
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Overdose of glutamic acid may increase the level of glutamate in the rat vitreous.
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In 103 eyes that had undergone advanced non-penetrating trabeculectomy, 20 eyes (19.4%) needed goniopuncture, and eight (7.7%) developed peripheral anterior synechia at three months or longer after operation.
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When a patient performed threshold N-30 testing of frequency-doubling technology three times, the mean deviation of during the second and third times was significantly better than during the first, but there was no difference between the second and third times.
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The inter-operator variation regarding HRT II measurements was very low, and the mean standard deviation was less than 20 mm.
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Nipradilol, a non-selective beta-adrenergic agent, dose-dependently protected apoptosis in rat retinal cells induced by injection of NMDA into the vitreous.
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The prognosis of visual field progression in normal-tension glaucoma statistically significantly depended on the intraocular pressure during follow-up, the presence of a disc hemorrhage, disc type (focal ischemic type), and the use or non-use of Ca++ blockers.
