advertisement

Top-six of the Glaucoma Group—Association of Ophthalmologists of Latvia Annual Meeting
Riga, Latvia, March 9–12, 2017

Guna Laganovska

Analysis of genetic polymorphisms in operated primary open-angle glaucoma patients in the Latvian population

1. Kristine Baumane, Riga
   A possible association of several single nucleotide polymorphisms (SNPs) with POAG was determined in the Latvian population. In total, three SNPs were genotyped in all samples: rs4656461 near the TMCO1 gene, rs1063192 near the CDKN2B gene and rs10483727 near SIX1/SIX6 gene. A small difference in the allele frequency of rs4656461 among different age groups was observed.
   
   
   
2. Oskars Gertners, Riga
   Anterior segment optical cocherence tomography is a useful tool which can be used to assess the ultrastructure of a filtering bleb after trabeculectomy. Postoperative intraocular pressure values can be linked with a few indicators in filtering bleb ultrastructure which show the overall outcome after trabeculectomy surgery.
   
   
   
3. Jekaterina Varlamova, Riga
   Accurate and precise intraocular pressure measurement is essential in detection and management of glaucoma. Reducing IOP has been shown to lessen progressive loss of the visual field. Goldmann applanation tonometer is regarded as the ‘gold standard’ however alternative methods have reduced risk of the possible cross infection.
   
   
   
4. Dāvis Raščevskis, Riga
   Thin cornea can be a marker of a structural weakness in the back of the eye ‒ at the optic nerve level. This might mean a greater likelihood of the damage occurring in the optic nerve and suggests that lower intraocular pressure is required.
   
   
   
   
5. Ēriks Elksnis, Gulbene
   The tear osmolarity is an important indicator of the ocular surface health. Long-term anti-glaucomatous eye drop use is accompanied not just by the discomfort symptoms of the ocular surface, but also with increased tear film osmolarity.
   
   
   
   
6. Ilze Lace, Riga
   Secondary glaucoma is one of the most common complications after silicone oil injection in vitreoretinal surgeries. In order to achieve good IOP control and prevent further IOP increase, early disease management and timely silicone oil removal is essential.