Top-six of the Glaucoma Group—Association of Ophthalmologists of Latvia Annual
Riga, Latvia, March 9–12, 2017
Analysis of genetic polymorphisms in operated primary open-angle glaucoma patients
in the Latvian population
Kristine Baumane, Riga
A possible association
of several single nucleotide polymorphisms (SNPs) with POAG was determined in
the Latvian population. In total, three SNPs were genotyped in all samples:
rs4656461 near the TMCO1 gene, rs1063192 near the CDKN2B gene and rs10483727
near SIX1/SIX6 gene. A small difference in the allele frequency of rs4656461
among different age groups was observed.
Anterior segment optical cocherence tomography is
a useful tool which can be used to assess the ultrastructure of a filtering
bleb after trabeculectomy. Postoperative intraocular pressure values can be
linked with a few indicators in filtering bleb ultrastructure which show the
overall outcome after trabeculectomy surgery.
Accurate and precise intraocular pressure measurement
is essential in detection and management of glaucoma. Reducing IOP has been
shown to lessen progressive loss of the visual field. Goldmann applanation tonometer
is regarded as the ‘gold standard’ however alternative methods have reduced
risk of the possible cross infection.
Thin cornea can be a marker of a structural weakness
in the back of the eye ‒ at the optic nerve level. This might mean a greater
likelihood of the damage occurring in the optic nerve and suggests that lower
intraocular pressure is required.
Ēriks Elksnis, Gulbene
The tear osmolarity is
an important indicator of the ocular surface health. Long-term anti-glaucomatous
eye drop use is accompanied not just by the discomfort symptoms of the ocular
surface, but also with increased tear film osmolarity.
Ilze Lace, Riga
Secondary glaucoma is one of the
most common complications after silicone oil injection in vitreoretinal surgeries.
In order to achieve good IOP control and prevent further IOP increase, early
disease management and timely silicone oil removal is essential.