News Flashes IGR 20-3

How difficult it is to place TM bypass stents in a consistent and effective manner, even in expert hands

Can OCTA parameters predict functional deterioration with high enough accuracy to be clinically useful for confirmation or forecasting of functional glaucoma progression?

The role of nighttime IOP fluctuations in glaucoma progression is not completely understood and investigated

Ab interno trabeculotomy was the most frequently chosen procedure (20%), followed by the Xen gel stent (19%)

Radial diffusivity in the optic radiation of glaucoma patients increased with visual field deficits and cortical thinning in a retinotopic manner

The eyeWatch is a potentially useful device for patients with refractory glaucoma who require a nonvalved glaucoma implant for glaucoma control

One concern is that almost 20% of patients in the Netarsudil arm discontinued treatment due to adverse events (AEs) compared to just over 2% in the timolol group

During a follow-up of 7.1 ± 0.8 years, a perimetric progression of GON was detected in 54% of the eyes with micro-DHs and in 28% of the 68 eyes without micro-DHs (P = 0.008)

The magnitude of effect of the systemic factors on the peripapillary VD measurements become clinically insignificant

Until we better understand the specific characteristics of IOP variation over time that confer risk of the development and/or progression of glaucoma, studies such as these are challenging to discuss in the context of clinical implications

There is a long-standing discussion whether changes in blood flow and oxygen metabolism are primary or secondary in glaucoma. Since this small-scale study was cross-sectional it does not contribute to the solution of this fundamental question

Patients with glaucoma may have less effective visual scanning strategies, reducing their ability to identify potential hazards

There is likely to be wide variation in bleb morphology produced with both procedures and it is not clear whether any patients had bleb needling which will inevitably affect morphology

This study adds to the growing literature suggesting that vascular insufficiency is associated with faster glaucomatous progression

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