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News Flashes IGR 22-4

The team demonstrated that experimental glaucoma constricts capillaries through calcium-dependent mechanisms that restricts ganglion cell blood supply

Early glaucoma sometimes results in central visual field damage that can be missed by the 24-2 GPA algorithm

Assessment of ROTA images improves diagnostic accuracy over current standards for glaucoma

The non-invasive ultrasonic approach is highly translatable to a clinical setting

Importantly, the sensors in all surviving patients were still functional after ten years

The long-term safety data provided from the pioneering ARGOS study demonstrate that implantable pressure sensors are a viable and well-tolerated method for obtaining IOP measurements outside of the office for management of glaucoma

The strongest risk factor for the development of OAG was high myopia, with a 7.3-fold increased incidence compared to emmetropic eyes

The measurement of ocular rigidity may have its own limitation

This study remains a pilot study, but it could hopefully encourage more engineering and clinical developments to better understand these interactions

Nerve fiber bundle visual field defects were common in both GON and NGON eyes and not found to be a helpful differentiating feature

Routine neuroimaging in patients with GON is costly, and rarely identifies a compressive lesion responsible for the associated visual field abnormality

SLT should be considered an alternative to repeat surgery in these eyes, especially given the exceedingly low risk of SLT versus repeat surgery

Clinicians may want to consider intensification of IOP lowering treatment when the central visual field is involved and CH is low

While central visual field progression was 0.07 dB/year faster per 1 mmHg lower CH (p < 0.001), the relationship did not prove to be significant for the total 24-degree visual field. Descent and Glaucoma

The current paper raises the promising possibility that fast progressors identified by OCTA are at higher risk of functional loss and may need more intensive observation and treatment

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