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Your Special Attention For IGR 10-2

A key role for calpains in retinal ganglion cell death

Y.H. Yücel and N. Gupta
Canadian Journal of Ophthalmology 2008; 43: 342-346

Abstract no. 535

'Double-hit' mechanisms of injury, such as glaucoma and comorbid cerebrovascular conditions, play a role in glaucomatous susceptibility and disease manifestations in young and aging populations at risk.


Extracellular matrix in the trabecular meshwork

T.S. Acott and M.J. Kelley
Experimental Eye Research 2008; 86: 543-561

Abstract no. 509

The extracellular matrix of the trabecular meshwork is thought to be important in regulating intraocular pressure (IOP) in both normal and glaucomatous eyes. It is relatively dynamic, undergoing constant turnover and remodeling.


Immunological mechanisms in glaucoma

F. Grus and D. Sun
Seminars in Immunopathology 2008; 30: 121-126

Abstract no. 562

Autoimmunity, including changes in autoantibody profiles and natural autoimmunity, have been identified in glaucoma and this may have implications for glaucoma detection.


Adverse events after intravitreal triamcinolone in patients with and without uveitis

A. Galor, R. Margolis, O.M.F. Brasil, V.L. Perez, P.K. Kaiser, J.E. Sears, C.Y. Lowder and S.D. Smith
Ophthalmology 2007; 114: 1912-1918

Abstract no. 1378

Patients with uveitis treated with IVTA should be counseled about risks of pressure elevation and cataract progression, and they should be monitored closely.


Role of optic nerve imaging in glaucoma clinical practice and clinical trials

D.S. Greenfield and R.N. Weinreb
American Journal of Ophthalmology 2008; 145: 598-603

Abstract no. 640

Advances in computerized imaging technology provide useful measures that assist the clinician in glaucoma diagnosis and monitoring and offer considerable opportunity for use as efficacy endpoints in clinical trials.


Comparison of HRT-3 Glaucoma Probability Score and Subjective Stereophotograph Assessment for Prediction of Progression in Glaucoma

L.M. Alencar, C. Bowd, R.N. Weinreb, L.M. Zangwill, P.A. Sample and F.A. Medeiros
Investigative Ophthalmology and Visual Science 2008; 49: 1898-1906

Abstract no. 895

HRT-3 Glaucoma Probability Score (GPS) values were predictive of conversion to glaucoma in patients with suspected glaucoma.


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