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Abstract #107785 Published in IGR 23-4
Probing mechanisms and improving management of glaucoma following Boston keratoprosthesis surgery
Geoffrion D; Koenekoop RK; Harissi-Dagher MActa Ophthalmologica 2023; 101: 242-243
Corneal blindness is a leading cause of visual impairment worldwide. The most common treatment is to replace the diseased cornea with standard corneal transplantation. In eyes at high risk of graft failure, the Boston keratoprosthesis type 1 (KPro) can be used to restore vision and is currently the most frequently used artificial cornea in the world. However, glaucoma is a well-known complication of KPro surgery and is the most important threat to vision in KPro-implanted eyes. This chronic disease is influenced by elevated intraocular pressure (IOP) and damages the optic nerve, leading to progressive vision loss. In KPro patients, glaucoma is highly prevalent and extremely challenging to manage, yet its exact cause remains unknown.
Department of Experimental Surgery, Faculty of Medicine, McGill University, Montreal, Quebec, Canada.
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