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WGC-2021

Abstract #82751 Published in IGR 20-4

Comparison of anterior chamber flare among different glaucoma surgeries

Tanito M; Manabe K; Mochiji M; Takai Y; Matsuoka Y
Clinical Ophthalmology 2019; 13: 1609-1612


PURPOSE: To compare postsurgical anterior chamber flare (ACF) among conventional (trabeculectomy, LEC) and novel (EX-PRESS Shunt, EXP) filtration surgeries and microhook ab interno trabeculotomy (μLOT), a novel minimally invasive glaucoma surgery (MIGS). SUBJECTS AND METHODS: This retrospective study included 125 primary open angle glaucoma eyes (89 consecutive subjects) treated with μLOT (n=38), LEC (n=12), or EXP (n=75). The intraocular pressure (IOP), numbers of antiglaucoma medication, and ACF at preoperatively and 2 weeks; 1, 3, and 6 months postoperatively were compared among the surgical groups using a mixed-effects regression model. RESULTS: The postoperative IOP (<0.0001) and medication use were significantly (<0.0001) lower in the LEC and EXP groups than with μLOT for up to 6 months postoperatively. The ACF differed significantly (=0.0004) among groups; the ACF was significantly higher (=0.0097, post-hoc Student's -test) with μLOT (33.6±52.8 pc/msec) than the EXP (15.7±19.9 pc/msec) at 2 weeks and was significantly (=0.0111, post-hoc -test) lower with μLOT (7.9±2.0 pc/msec) than LEC (12.0±6.1 pc/msec) at 6 months. CONCLUSION: Considering our observation, although its clinical significance is unclear, not all MIGS are minimally invasive regarding early postsurgical inflammation.

Full article

Classification:

12.1 General management, indication (Part of: 12 Surgical treatment)
6.3.1 Anterior segment (Part of: 6 Clinical examination methods > 6.3 Biomicroscopy (slitlamp))



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WGC-2021