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Abstract #13608 Published in IGR 8-2
GDxVCC of retinal nerve fibre layer in perimetrically unaffected eyes of chronic angle closure glaucoma patients
Hu M-M; Duan X-CInternational Journal of Ophthalmology 2006; 6: 102-106
AIM: To compare scanning laser polarimetry (GDxVCC system) measurements of retinal nerve fiber layer (RNFL) thickness in perimetrically unaffected eyes of chronic angle closure glaucoma patients with those in their fellow eyes with visual field loss and eyes of healthy subjects. METHODS: Twenty-six chronic angle closure glaucoma patients with a reproducible visual field defect in one eye and a normal visual field in the other one (i.e., ≤ 1 visual field test point below the 5% probability level) were divided into two groups, namely, a CACG group with normal visual field and a CACG group with visual field loss. Twenty-four healthy subjects (forty-eight eyes) were treated as age-matched controls. All subjects were measured in both eyes with the GDxVCC. Datas were analysed. RNFL parameters of both CACG groups and the control group were compared. RESULTS: Compared with control group, the RNFL of the CACG group with notmal visual field was thinner, but it was thicker than that of the CACG group with visual field loss. All parameters of CACG group showed statistically significant differences compared with CACG group or control group. The parameters of Inferior Average and NFI showed no significant differences between CACG group and control group (P = 0.073, P = 0.054) but significant differences in parameters of TSNIT Average, Superior Average and TSNIT Std Dev respectively (P = 0.002, P = 0.002, P = 0.010). CONCLUSION: GDxVCC can earlier detect glaucomatous RNFL damage and be used both in the follow-up and the pursue of perimetrically unaffected eyes in chronic angle closure glaucoma patients. LA: Chinese
Dr. M.-M. Hu, Department of Ophthalmology, Hospital of Xiangya Medical College, Central-South University, Changsha 410011 Hunan Province, China
Classification:
6.9.1 Laser scanning (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis)
9.3.2 Chronic primary angle closure glaucoma (pupillary block) (Part of: 9 Clinical forms of glaucomas > 9.3 Primary angle closure glaucomas)