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Abstract #8406 Published in IGR 5-1
Reproducibility of evaluation of optic disc change for glaucoma with stereo optic disc photographs
Zeyen T; Miglior S; Pfeiffer N; Cunha-Vaz J; Adamsons I; European Glaucoma Prevention Study GroupOphthalmology 2003; 110: 340-344
PURPOSE: To determine the reproducibility of the assessment of glaucomatous changes in serial optic disc stereo-slides. DESIGN: Masked interobserver variability study. PARTICIPANTS: Serial optic disc stereo-slides taken from 40 patients. METHODS: Three independent ophthalmologists evaluated the change in a set of two serial 20° optic disc color stereo-slides from 40 patients. This test set was not from European Glaucoma Prevention Study (EGPS) patients. Each observer performed two evaluations at least 30 days apart and was masked for the temporal sequence of the slides and his or her previous evaluation. Each patient was graded as changed or stable by two-out-of-three agreement. A kappa statistic was used to calculate the intra- and interobserver reproducibility, as well as the assignment reproducibility (first consensus versus second consensus). The same procedure was followed to test the reproducibility when another experienced ophthalmologist was added to one of the three reading centers. MAIN OUTCOME MEASURES: Reproducibility in evaluating glaucomatous optic disc changes. RESULTS: The intraobserver reproducibility (95% confidence interval (CI)) in the evaluation of change ranged between 0.79 (0.45-1.14) and 1.00 (0.69-1.31). The interobserver reproducibility (95% CI) in the evaluation of change ranged between 0.45 (0.15-0.75) and 0.75 (0.44-1.06). The assignment reproducibility (first consensus versus second consensus in the evaluation of change) between the senior EGPS readers was 0.94 (0.63-1.25). The assignment reproducibility when another experienced ophthalmologist replaced one of the readers was 0.94 (0.63-1.25). CONCLUSIONS: The assignment reproducibility of three expert readers looking for glaucomatous change in serial optic disc stereo-slides was excellent, and remained so when one of the three experts was replaced by another experienced reader.
Dr. T. Zeyen, K.U. Leuven, St Rafael Hospital, Kapucijnenvoer 33, B-3000 Leuven, Belgium
Classification:
2.14 Optic disc (Part of: 2 Anatomical structures in glaucoma)
6.8.2 Posterior segment (Part of: 6 Clinical examination methods > 6.8 Photography)